Cosmids
A Cosmids vector is a hybrid between a plasmid and a phage λ vector. A classic example of a Cosmids vector is c2RB, which has an origin of replication and a cloning site and carries an antibiotic resistance gene. Like phage λ vectors, Cosmids vectors encode the cos sequence required to package DNA into a λ capsid. A Cosmids is a type of hybrid plasmid that contains the lambda phage cos sequence. They are often used as cloning vectors in genetic engineering. Cosmids vectors are developed by combining features of plasmid vectors and bacteriophage vectors. The origin of replication, multiple cloning sites and selectable markers are obtained from the plasmid and only the aggregation site or cos site region is taken from the lambda phage.
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